Analytical Determination of Heavy Metals in Human Seminal Plasma—A Systematic Review
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Título: | Analytical Determination of Heavy Metals in Human Seminal Plasma—A Systematic Review |
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Autor/es: | López-Botella, Andrea | Sánchez, Raquel | Paul, Raiza | Aizpurua, Jon | Gómez-Torres, María José | Todolí Torró, José Luis |
Grupo/s de investigación o GITE: | Grupo de Inmunología, Biología Celular y del Desarrollo | Análisis de Polímeros y Nanomateriales |
Centro, Departamento o Servicio: | Universidad de Alicante. Departamento de Biotecnología | Universidad de Alicante. Departamento de Química Analítica, Nutrición y Bromatología |
Palabras clave: | Heavy metals | Seminal plasma | Environmental factors | Lifestyle factors | Seminal biomarkers | Male infertility | Endocrine-disrupting compounds |
Fecha de publicación: | 31-mar-2023 |
Editor: | MDPI |
Cita bibliográfica: | López-Botella A, Sánchez R, Paul R, Aizpurua J, Gómez-Torres MJ, Todolí-Torró J-L. Analytical Determination of Heavy Metals in Human Seminal Plasma—A Systematic Review. Life. 2023; 13(4):925. https://doi.org/10.3390/life13040925 |
Resumen: | Infertility is a growing concerning health problem affecting around 15% of couples worldwide. Conventional semen parameters have limited accuracy for male infertility potential determination. Current advances in the understanding of male infertility indicate that environmental and occupational exposure to chemical contaminants are important etiological factors leading to infertility problems. In this context, some heavy metals (HMs) can be considered as endocrine-disrupting compounds (EDCs), thus altering the seminal quality. This systematic review aims to summarize the key points to detect and quantify HMs in human seminal plasma (SP) and the involved analytical tools. Our results showed that that for HM quantification, atomic absorption spectroscopy (AAS) and inductively coupled plasma (ICP) were the most employed techniques while Zn, Cd, Pb, and Cr were the analytes most often detected. Fast, reliable, and sensitive quantification of EDCs in SP could be important for the development of accurate diagnostic and preventive strategies to address male infertility towards providing personalized therapy. |
Patrocinador/es: | Funded by PID2021-127566NB-I00 (Ministerio de Ciencia e Innovación). A.L.-B. is supported by the European Social Fund and Generalitat Valenciana under a PhD contract (ACIF-2021/243). |
URI: | http://hdl.handle.net/10045/133351 |
ISSN: | 2075-1729 |
DOI: | 10.3390/life13040925 |
Idioma: | eng |
Tipo: | info:eu-repo/semantics/article |
Derechos: | © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
Revisión científica: | si |
Versión del editor: | https://doi.org/10.3390/life13040925 |
Aparece en las colecciones: | INV - Grupo de Inmunología - Artículos de Revistas INV - NANOBIOPOL - Artículos de Revistas |
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Lopez-Botella_etal_2023_Life.pdf | 3,29 MB | Adobe PDF | Abrir Vista previa | |
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