Lateral spread of dose distribution by therapeutic proton beams in liquid water

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Title: Lateral spread of dose distribution by therapeutic proton beams in liquid water
Authors: Abril, Isabel | Vera Gomis, Pablo de | García Molina, Rafael | Kyriakou, Ioanna | Emfietzoglou, Dimitris
Research Group/s: Interacción de Partículas Cargadas con la Materia
Center, Department or Service: Universidad de Alicante. Departamento de Física Aplicada
Keywords: Hadron therapy | Proton beam | Bragg peak | Liquid water | Depth-dose profile
Knowledge Area: Física Aplicada
Issue Date: 1-Jun-2015
Publisher: Elsevier
Citation: Nuclear Instruments and Methods in Physics Research Section B. 2015, 352: 176-180. doi:10.1016/j.nimb.2014.11.100
Abstract: We have calculated the lateral spread of the dose distribution of protons in liquid water by means of the SEICS (Simulation of Energetic Ions and Clusters through Solids) code, which properly accounts for the electronic stopping force (including energy-loss straggling), multiple elastic scattering with the target nuclei, dynamical electron charge-exchange processes and nuclear fragmentation reactions between the projectile and the nuclei of the target. Due to the multiple elastic scattering processes part of the proton energy may be deposited at a given lateral distance from the initial beam direction, which is quantified by the root mean square radius (rrms). We find in our simulations that the rrms follows a parabolic dependence as a function of the depth in the target and the quotient between the rrms at the Bragg peak and the depth of the Bragg peak is around 3% independently of the proton energy. A rather good agreement is obtained when comparing our results of rrms with experimental data and with other models.
Sponsor: We thank the financial support from the Spanish Ministerio de Economía y Competitividad and the European Regional Development Fund within the Project No. FIS2010-17225. PdV acknowledges financial support from the European FP7-PEOPLE-ITN ARGENT Project. This paper is part of the COST Action MP1002, Nanoscale Insights into Ion Beam Cancer Therapy.
ISSN: 0168-583X (Print) | 1872-9584 (Online)
DOI: 10.1016/j.nimb.2014.11.100
Language: eng
Type: info:eu-repo/semantics/article
Rights: © 2014 Elsevier B.V.
Peer Review: si
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Appears in Collections:INV - IPCM - Artículos de Revistas
Research funded by the EU

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