Lipidomic approach in young adult triathletes: effect of supplementation with a polyphenols-rich juice on neuroprostane and F2-dihomo-isoprostane markers
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Título: | Lipidomic approach in young adult triathletes: effect of supplementation with a polyphenols-rich juice on neuroprostane and F2-dihomo-isoprostane markers |
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Autor/es: | García-Flores, Libia Alejandra | Medina, Sonia | Oger, Camille | Galano, Jean-Marie | Durand, Thierry | Cejuela, Roberto | Martínez Sanz, José Miguel | Ferreres, Federico | Gil-Izquierdo, Ángel |
Grupo/s de investigación o GITE: | Research in Physical Education, Fitness and Performance (RIPEFAP) | Grupo de Investigación en Alimentación y Nutrición (ALINUT) |
Centro, Departamento o Servicio: | Universidad de Alicante. Departamento de Didáctica General y Didácticas Específicas | Universidad de Alicante. Departamento de Enfermería |
Palabras clave: | Polyphenols | Oxidative stress | F4-neuroprostanes | F2-dihomo-isoprostanes | Aronia-Citrus Juice | Athletes | Biomarkers |
Área/s de conocimiento: | Educación Física y Deportiva | Enfermería |
Fecha de publicación: | 30-ago-2016 |
Editor: | Royal Society of Chemistry |
Cita bibliográfica: | Food & Function. 2016, 7: 4343-4355. doi:10.1039/C6FO01000H |
Resumen: | The aim of the this study was to determine the effect of a polyphenols-rich juice (aronia-citrus juice, ACJ) on F4-neuroprostanes and F2-dihomo-isoprostanes—markers of oxidative stress associated with the central nervous system (CNS)—in 16 elite triathletes under a controlled diet for triathlon training (145 days). In the triathletes, a decrease of the lipid peroxidation markers after ACJ intake, associated with neuronal membrane degradation (10-epi-10-F4t-neuroprostane and 10-F4t-neuroprostane), was observed when compared with placebo stage values. Regarding the F2-dihomo-isoprostanes, a significant decrease of the neuromotor system damage biomarkers (17-F2t-dihomo-isoprostane) with an increase of training load during the study was observed, although the decrease of the load training at the last stage showed a significant increase of the values of ent-7-(RS)-7-F2t-dihomo-IsoP, suggesting a possible role in adaptation post-training. On the other hand, the changes in the excretion of 17-epi-17-F2t-dihomo-IsoP provided a positive connection between physical exercise and ACJ intake. Thus, the results showed in this clinical study in young triathletes will help to elucidate novel interactions and mechanisms between the excretion of lipid peroxidation metabolites from CNS, supplementation of polyphenols-rich juice in the diet and physical exercise during a training season. |
Patrocinador/es: | This study was supported by the project AGL2011-23690 (CICYT) (Spanish Ministry of Economy and Competitiveness). This work has been partially funded by the “Fundación Séneca de la Región de Murcia” Grupo de Excelencia 19900/GERM/15. LAGF was granted a pre-doctoral FPI fellowship (BES2012-060185) by the Spanish government. |
URI: | http://hdl.handle.net/10045/59027 |
ISSN: | 2042-6496 (Print) | 2042-650X (Online) |
DOI: | 10.1039/C6FO01000H |
Idioma: | eng |
Tipo: | info:eu-repo/semantics/article |
Derechos: | © The Royal Society of Chemistry 2016 |
Revisión científica: | si |
Versión del editor: | http://dx.doi.org/10.1039/C6FO01000H |
Aparece en las colecciones: | INV - ALINUT - Artículos de Revistas INV - SCAPE - Artículos de Revistas |
Archivos en este ítem:
Archivo | Descripción | Tamaño | Formato | |
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2016_Garcia-Flores_etal_FoodFunct_final.pdf | Versión final (acceso restringido) | 840,84 kB | Adobe PDF | Abrir Solicitar una copia |
2016_Garcia-Flores_etal_FoodFunct_accepted.pdf | Accepted Manuscript (acceso abierto) | 1,24 MB | Adobe PDF | Abrir Vista previa |
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