Peptides with biological and technofunctional properties produced by bromelain hydrolysis of proteins from different sources: A review
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Título: | Peptides with biological and technofunctional properties produced by bromelain hydrolysis of proteins from different sources: A review |
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Autor/es: | Tacias-Pascacio, Veymar G. | Castañeda-Valbuena, Daniel | Tavano, Olga Luisa | Berenguer-Murcia, Ángel | Torrestina-Sánchez, Beatriz | Fernández Lafuente, Roberto |
Grupo/s de investigación o GITE: | Materiales Carbonosos y Medio Ambiente |
Centro, Departamento o Servicio: | Universidad de Alicante. Departamento de Química Inorgánica | Universidad de Alicante. Instituto Universitario de Materiales |
Palabras clave: | Protein hydrolysis | Combiproteases | Hydrolysis degree |
Fecha de publicación: | 6-oct-2023 |
Editor: | Elsevier |
Cita bibliográfica: | International Journal of Biological Macromolecules. 2023, 253(Part 5): 127244. https://doi.org/10.1016/j.ijbiomac.2023.127244 |
Resumen: | Bromelains are cysteine peptidases with endopeptidase action (a subfamily of papains), obtained from different parts of vegetable belonging to the Bromeliaceae family. They have some intrinsic medical activity, but this review is focused on their application (individually or mixed with other proteases) to produce bioactive peptides. When compared to other proteases, perhaps due to the fact that they are commercialized as an extract containing several proteases, the hydrolysates produced by this enzyme tends to have higher bioactivities than other common proteases. The peptides and the intensity of their final properties depend on the substrate protein and reaction conditions, being the degree of hydrolysis a determining parameter (but not always positive or negative). The produced peptides may have diverse activities such as antioxidant, antitumoral, antihypertensive or antimicrobial ones, among others or they may be utilized to improve the organoleptic properties of foods and feeds. Evolution of the use of this enzyme in this application is proposed to be based on a more intense direct application of Bromeliaceae extract, without the cost associated to enzyme purification, and the use of immobilized biocatalysts of the enzyme by simplifying the enzyme recovery and reuse, and also making the sequential hydrolysis using diverse proteases possible. |
Patrocinador/es: | This work was funded by Ministerio de Ciencia e Innovación and Agencia Estatal de Investigación (Spanish Government) (project PID2022-136535OB-I00 and MCIN/AEI/10.13039/501100011033/) and by FEDER A Way of Making Europe funds (project PID2021-123079OB-I00), and Generalitat Valenciana (CIPROM/2021/70). The supports from Técnologico Nacional de Mexico (grant number 16944.23-P is also gratefully recognized. |
URI: | http://hdl.handle.net/10045/138014 |
ISSN: | 0141-8130 (Print) | 1879-0003 (Online) |
DOI: | 10.1016/j.ijbiomac.2023.127244 |
Idioma: | eng |
Tipo: | info:eu-repo/semantics/article |
Derechos: | © 2023 Elsevier B.V. |
Revisión científica: | si |
Versión del editor: | https://doi.org/10.1016/j.ijbiomac.2023.127244 |
Aparece en las colecciones: | INV - MCMA - Artículos de Revistas |
Archivos en este ítem:
Archivo | Descripción | Tamaño | Formato | |
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Tacias-Pascacio_etal_2023_IntJBiolMacromol_final.pdf | Versión final (acceso restringido) | 1,38 MB | Adobe PDF | Abrir Solicitar una copia |
Tacias-Pascacio_etal_2023_IntJBiolMacromol_revised.pdf | Embargo 12 meses (acceso abierto: 7 oct. 2024) | 3,86 MB | Adobe PDF | Abrir Solicitar una copia |
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