Ficin: A protease extract with relevance in biotechnology and biocatalysis
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Título: | Ficin: A protease extract with relevance in biotechnology and biocatalysis |
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Autor/es: | Morellon-Sterling, Roberto | El-Siar, Hocine | Tavano, Olga Luisa | Berenguer-Murcia, Ángel | Fernández Lafuente, Roberto |
Grupo/s de investigación o GITE: | Materiales Carbonosos y Medio Ambiente |
Centro, Departamento o Servicio: | Universidad de Alicante. Departamento de Química Inorgánica | Universidad de Alicante. Instituto Universitario de Materiales |
Palabras clave: | Proteases | Proteolysis | Synthesis of peptides | Bioactive peptides | Protease immobilization | Ficin |
Área/s de conocimiento: | Química Inorgánica |
Fecha de publicación: | 1-nov-2020 |
Editor: | Elsevier |
Cita bibliográfica: | International Journal of Biological Macromolecules. 2020, 162: 394-404. doi:10.1016/j.ijbiomac.2020.06.144 |
Resumen: | Due to the problems raised by the use of animal or microbial recombinant proteases, the use of proteases from vegetable origin is becoming increasingly popular.. Among them, sulfidryl proteases have a special interest. Ficin is an outstanding example of this kind of proteases. This paper aims to be to make a comprehensive review of the recent uses of this enzyme, including for example protein hydrolysis, the production of bioactive peptides and antibodies fragments (researchers point that ficin results are more reproducible than using other proteases), meat tenderization, milk coagulations in cheese making or peptide synthesis. Efforts to get industrial immobilized biocatalysts of the enzyme will be also described. The review shows the huge potential and brilliant prospect that this enzyme can have in the near future. |
Patrocinador/es: | We gratefully recognize the support from the Ministerio de Ciencia e Innovación from Spanish Government (project number CTQ2017-86170-R). The FPU fellowship (Ministerio de Educacion) for Mr. Morellon–Sterling and the fellowship for Mr. Siar from the Algerian Ministry of Higher Education and Scientific Research are also thanked. |
URI: | http://hdl.handle.net/10045/107974 |
ISSN: | 0141-8130 (Print) | 1879-0003 (Online) |
DOI: | 10.1016/j.ijbiomac.2020.06.144 |
Idioma: | eng |
Tipo: | info:eu-repo/semantics/article |
Derechos: | © 2020 Elsevier B.V. |
Revisión científica: | si |
Versión del editor: | https://doi.org/10.1016/j.ijbiomac.2020.06.144 |
Aparece en las colecciones: | INV - MCMA - Artículos de Revistas |
Archivos en este ítem:
Archivo | Descripción | Tamaño | Formato | |
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Morellon-Sterling_etal_2020_IntJBioMacromol_final.pdf | Versión final (acceso restringido) | 754,22 kB | Adobe PDF | Abrir Solicitar una copia |
Morellon-Sterling_etal_2020_IntJBioMacromol_accepted.pdf | Accepted Manuscript (acceso abierto) | 769,23 kB | Adobe PDF | Abrir Vista previa |
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