Chapter Seven - The effects of stress on cardiovascular disease and Alzheimer's disease: Physical exercise as a counteract measure
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Título: | Chapter Seven - The effects of stress on cardiovascular disease and Alzheimer's disease: Physical exercise as a counteract measure |
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Autor/es: | Sanchis-Soler, Gema | Tortosa-Martínez, Juan | Manchado, Carmen | Cortell-Tormo, Juan M. |
Grupo/s de investigación o GITE: | Research in Physical Education, Fitness and Performance (RIPEFAP) |
Centro, Departamento o Servicio: | Universidad de Alicante. Departamento de Didáctica General y Didácticas Específicas |
Palabras clave: | Dementia | Physical activity | Cognition | Cortisol | HPA axis | Cardiovascular health |
Área/s de conocimiento: | Didáctica de la Expresión Corporal | Educación Física y Deportiva |
Fecha de publicación: | 2020 |
Editor: | Elsevier |
Cita bibliográfica: | International Review of Neurobiology. 2020, 152: 157-193. doi:10.1016/bs.irn.2020.01.002 |
Resumen: | AD is a complicated multi-systemic neurological disorder that involves different biological pathways. Several risk factors have been identified, including chronic stress. Chronic stress produces an alteration in the activity of the hypothalamic pituitary adrenal (HPA) system, and the autonomic nervous system (ANS), which over time increase the risk of AD and also the incidence of cardiovascular disease (CVD) and risk factors, such as hypertension, obesity and type 2 diabetes, associated with cognitive impairment and AD. Considering the multi-factorial etiology of AD, understanding the complex interrelationships between different risk factors is of potential interest for designing adequate strategies for preventing, delaying the onset or slowing down the progression of this devastating disease. Thus, in this review we will explore the general mechanisms and evidence linking stress, cardiovascular disease and AD, and discuss the potential benefits of physical activity for AD by counteracting the negative effects of chronic stress, CVD and risk factors. |
URI: | http://hdl.handle.net/10045/107157 |
ISSN: | 0074-7742 (Print) | 2162-5514 (Online) |
DOI: | 10.1016/bs.irn.2020.01.002 |
Idioma: | eng |
Tipo: | info:eu-repo/semantics/article |
Derechos: | © 2020 Elsevier Inc. |
Revisión científica: | si |
Versión del editor: | https://doi.org/10.1016/bs.irn.2020.01.002 |
Aparece en las colecciones: | INV - SCAPE - Artículos de Revistas INV - HEALTH-TECH - Artículos de Revistas |
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Sanchis-Soler_etal_2020_IntRevNeurobiology_final.pdf | Versión final (acceso restringido) | 350,41 kB | Adobe PDF | Abrir Solicitar una copia |
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