Decarboxylative Giese-Type Reaction of Carboxylic Acids Promoted by Visible Light: A Sustainable and Photoredox-Neutral Protocol
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http://hdl.handle.net/10045/65512
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| Campo DC | Valor | Idioma |
|---|---|---|
| dc.contributor | Catálisis Estereoselectiva en Síntesis Orgánica (CESO) | es_ES |
| dc.contributor.author | Ramírez, Nieves P. | - |
| dc.contributor.author | Gonzalez-Gomez, Jose C. | - |
| dc.contributor.other | Universidad de Alicante. Departamento de Química Orgánica | es_ES |
| dc.contributor.other | Universidad de Alicante. Instituto Universitario de Síntesis Orgánica | es_ES |
| dc.date.accessioned | 2017-04-26T10:38:24Z | - |
| dc.date.available | 2017-04-26T10:38:24Z | - |
| dc.date.issued | 2017-04-18 | - |
| dc.identifier.citation | European Journal of Organic Chemistry. 2017, 15: 2154-2163. doi:10.1002/ejoc.201601478 | es_ES |
| dc.identifier.issn | 1434-193X (Print) | - |
| dc.identifier.issn | 1099-0690 (Online) | - |
| dc.identifier.uri | http://hdl.handle.net/10045/65512 | - |
| dc.description.abstract | We describe herein a transition-metal-free method for the decarboxylative generation of radicals from carboxylic acids and their 1,4-addition to Michael acceptors. The Fukuzumi catalyst (9-mesitylene-10-methylacridinium perchlorate, [Acr-Mes]ClO4) enabled this transformation under visible-light irradiation at room temperature with CO2 as the only byproduct. The scope and limitations of this protocol were examined by using a range of Michael acceptors (15 examples) and carboxylic acids (18 examples). The use of 3-hydroxypivalic acid in this protocol allowed the straightforward formation of a diastereomerically pure δ-lactone. Moreover, when a homoallylic acid was used, a radical cascade reaction took place with the formation of three C–C bonds. | es_ES |
| dc.description.sponsorship | We thank the Ministerio de Economia y Competitividad (CTQ2015-66624-P) and the University of Alicante (VIGROB-173) for financial support. N. P. R. thanks the Institute of Organic Synthesis (ISO) for a grant. | es_ES |
| dc.language | eng | es_ES |
| dc.publisher | Wiley-VCH Verlag GmbH & Co. KGaA | es_ES |
| dc.rights | © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim | es_ES |
| dc.subject | Carboxylic acids | es_ES |
| dc.subject | Synthetic methods | es_ES |
| dc.subject | Radical reactions | es_ES |
| dc.subject | Photocatalysis | es_ES |
| dc.subject | Sustainable chemistry | es_ES |
| dc.subject.other | Química Orgánica | es_ES |
| dc.title | Decarboxylative Giese-Type Reaction of Carboxylic Acids Promoted by Visible Light: A Sustainable and Photoredox-Neutral Protocol | es_ES |
| dc.type | info:eu-repo/semantics/article | es_ES |
| dc.peerreviewed | si | es_ES |
| dc.identifier.doi | 10.1002/ejoc.201601478 | - |
| dc.relation.publisherversion | http://dx.doi.org/10.1002/ejoc.201601478 | es_ES |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
| dc.relation.projectID | info:eu-repo/grantAgreement/MINECO//CTQ2015-66624-P | - |
| Aparece en las colecciones: | INV - CESO - Artículos de Revistas | |
Archivos en este ítem:
| Archivo | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
 2017_Ramirez_Gonzalez_EurJOC_final.pdf | Versión final (acceso restringido) | 1,85 MB | Adobe PDF | Abrir Solicitar una copia |
 2017_Ramirez_Gonzalez_EurJOC_accepted.pdf | Accepted Manuscript (acceso abierto) | 2,33 MB | Adobe PDF | Abrir Vista previa |
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