Intra-session repeatability of iridocorneal angle measurements provided by a Scheimpflug photography-based system in healthy eyes

Abstract

Purpose: The purpose of this study was to evaluate intra-session repeatability of measurements of the iridocorneal angle at different meridians in the nasal and temporal areas in healthy eyes using the Sirius Scheimpflug photography-based system in glaucoma analysis mode. Methods: A total of 43 eyes of 43 patients ranging in age from 36 to 79 years were enrolled in the study. All eyes received a comprehensive ophthalmologic examination including a complete anterior segment analysis with the Costruzione Strumenti Oftalmici [CSO] Sirius system. Three consecutive measurements of nasal and temporal angles at 0°, ±10°, ±20°, and ±30° meridians were obtained in order to assess the intra-session repeatability of iridocorneal angle measurements provided by the device using the glaucoma analysis mode. Within-subject standard deviation (Sw), coefficient of variation (CV), and intraclass correlation coefficient (ICC) values were calculated. Results: The mean Sw was 1.07 ± 1.09°, 1.22 ± 1.53°, 0.66 ± 0.51°, 0.86 ± 0.57°, 0.68 ± 0.65°, 0.84 ± 0.68°, and 0.91 ± 0.70° at the temporal 30°, 20°, 10°, 0°, −10°, −20°, and −30° positions, respectively. Mean Sw was 3.13 ± 3.15°, 3.43 ± 3.63°, 2.75 ± 2.29°, 2.19 ± 1.55°, 1.90 ± 1.49°, 2.14 ± 1.74°, and 2.24 ± 2.06° at the temporal −30°, −20°, −10°, 0°, 10°, 20°, and 30° positions, respectively. Mean CV ranged from 1.36 ± 1.05 % (nasal 0° position) to 10.92 ± 13.95 % (nasal −20° position). ICC values ranged from 0.778 to 0.972. Conclusions: The glaucoma analysis mode of the Sirius system provides consistent measurements of the iridocorneal angle at different meridians in healthy eyes, with slightly less consistency for nasal measurements. It may be considered a clinically useful non-invasive technique for the detection of potentially occludable angles.