Evidences of adenine–thymine Interactions at gold electrodes interfaces as provided by in-situ infrared spectroscopy

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Title: Evidences of adenine–thymine Interactions at gold electrodes interfaces as provided by in-situ infrared spectroscopy
Authors: Rueda Rueda, Manuela | Prieto Dapena, Francisco | Álvarez Malmagro, Julia | Rodes García, Antonio
Research Group/s: Grupo de Espectroelectroquímica y Modelización (GEM)
Center, Department or Service: Universidad de Alicante. Departamento de Química Física | Universidad de Alicante. Instituto Universitario de Electroquímica
Keywords: Adenine | Thymine | Adsorption | Gold electrodes | ATR-SEIRAS
Knowledge Area: Química Física
Issue Date: Oct-2013
Publisher: Elsevier
Citation: Electrochemistry Communications. 2013, 35: 53-56. doi:10.1016/j.elecom.2013.07.026
Abstract: The co-adsorption of complementary DNA bases adenine and thymine on gold thin-film electrodes from 0.1 M HClO4 solutions in H2O and D2O is studied by surface-enhanced infrared absorption spectroscopy in the attenuated total reflection mode (ATR-SEIRAS). The comparison of the spectra in the range 1750–1550 cm− 1 for co-adsorbed adenine and thymine at controlled potentials to those of the individual adsorbed bases shows the enhancement of the signals associated to the vibration modes of adenine and the inhibition of those of thymine. The results can be explained by invoking the rearrangement of both molecules on the electrode surface in order to facilitate the Watson–Crick (W–C) and/or Hoogsteen (HG) interactions between the bases. The co-adsorption seems to be a cooperative process in which a low surface concentration of each base can induce the rearrangement of the complementary base molecules on the surface.
Sponsor: Financial support from Ministerio de Educación y Ciencia (Spain) (Projects CTQ2010-19823 and CTQ2009-13142 and a FPU-grant to JA), Junta de Andalucía (Grupo FQM202) and Generalitat Valenciana (ACOMP/2011/200) are greatly acknowledged.
URI: http://hdl.handle.net/10045/39116
ISSN: 1388-2481 (Print) | 1873-1902 (Online)
DOI: 10.1016/j.elecom.2013.07.026
Language: eng
Type: info:eu-repo/semantics/article
Peer Review: si
Publisher version: http://dx.doi.org/10.1016/j.elecom.2013.07.026
Appears in Collections:INV - GEM - Artículos de Revistas

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