Ionization of biomolecular targets by ion impact: input data for radiobiological applications
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Campo DC | Valor | Idioma |
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dc.contributor | Interacción de Partículas Cargadas con la Materia | es |
dc.contributor.author | Vera Gomis, Pablo de | - |
dc.contributor.author | Abril, Isabel | - |
dc.contributor.author | García Molina, Rafael | - |
dc.contributor.author | Solov'yov, Andrey V. | - |
dc.contributor.other | Universidad de Alicante. Departamento de Física Aplicada | es |
dc.date.accessioned | 2014-03-03T12:17:51Z | - |
dc.date.available | 2014-03-03T12:17:51Z | - |
dc.date.issued | 2013 | - |
dc.identifier.citation | Journal of Physics: Conference Series. 2013, 438: 012015. doi:10.1088/1742-6596/438/1/012015 | es |
dc.identifier.issn | 1742-6588 (Print) | - |
dc.identifier.issn | 1742-6596 (Online) | - |
dc.identifier.uri | http://hdl.handle.net/10045/35826 | - |
dc.description.abstract | In this work we review and further develop a semiempirical model recently proposed for the ion impact ionization of complex biological media. The model is based on the dielectric formalism, and makes use of a semiempirical parametrization of the optical energy-loss function of bioorganic compounds, allowing the calculation of single and total ionization cross sections and related quantities for condensed biological targets, such as liquid water, DNA and its components, proteins, lipids, carbohydrates or cell constituents. The model shows a very good agreement with experimental data for water, adenine and uracil, and allows the comparison of the ionization efficiency of different biological targets, and also the average kinetic energy of the ejected secondary electrons. | es |
dc.description.sponsorship | Financial support from the Spanish Ministerio de Economía y Competitividad and the European Regional Development Fund within the Project FIS2010–17225 and from the Conselleria d’Educació, Cultura i Esport de la Generalitat Valenciana for granting PdV within the VALi+d program. Support from the COST Action MP1002 NanoIBCT is greatfully acknowledged. | es |
dc.language | eng | es |
dc.publisher | IOP Publishing | es |
dc.rights | Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. Published under licence by IOP Publishing Ltd | es |
dc.subject | Effects of ionizing radiation on biological systems | es |
dc.subject | Proteins | es |
dc.subject | Dosimetry/exposure assessment | es |
dc.subject | Diseases | es |
dc.subject | Reactions in complex biological systems | es |
dc.subject | Nucleic acids | es |
dc.subject.other | Física Aplicada | es |
dc.title | Ionization of biomolecular targets by ion impact: input data for radiobiological applications | es |
dc.type | info:eu-repo/semantics/article | es |
dc.peerreviewed | si | es |
dc.identifier.doi | 10.1088/1742-6596/438/1/012015 | - |
dc.relation.publisherversion | http://dx.doi.org/10.1088/1742-6596/438/1/012015 | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.relation.projectID | info:eu-repo/grantAgreement/MICINN//FIS2010-17225 | - |
Aparece en las colecciones: | INV - IPCM - Artículos de Revistas |
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