Potential Development of Vitrified Immature Human Oocytes: Influence of the Culture Medium and the Timing of Vitrification
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Campo DC | Valor | Idioma |
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dc.contributor | Grupo de Inmunología, Biología Celular y del Desarrollo | es_ES |
dc.contributor.author | Peinado, Irene | - |
dc.contributor.author | Moya, Isabel | - |
dc.contributor.author | García-Valverde, Laura M. | - |
dc.contributor.author | Francés, Raquel | - |
dc.contributor.author | Ribes, Rosana | - |
dc.contributor.author | Polo, Patrocinio | - |
dc.contributor.author | Gómez-Torres, María José | - |
dc.contributor.author | Monzó, Ana | - |
dc.contributor.other | Universidad de Alicante. Departamento de Biotecnología | es_ES |
dc.date.accessioned | 2023-01-09T09:55:16Z | - |
dc.date.available | 2023-01-09T09:55:16Z | - |
dc.date.issued | 2022-12-27 | - |
dc.identifier.citation | Peinado I, Moya I, García-Valverde L, Francés R, Ribes R, Polo P, Gómez-Torres MJ, Monzó A. Potential Development of Vitrified Immature Human Oocytes: Influence of the Culture Medium and the Timing of Vitrification. International Journal of Molecular Sciences. 2023; 24(1):417. https://doi.org/10.3390/ijms24010417 | es_ES |
dc.identifier.issn | 1422-0067 | - |
dc.identifier.uri | http://hdl.handle.net/10045/130839 | - |
dc.description.abstract | How does the in vitro maturation (IVM) medium and the vitrification procedure affect the survival of germinal vesicle (GV) oocytes obtained from stimulated cycles and their development to the blastocyst stage? In total, 1085 GV human oocytes were obtained after women underwent a cycle of controlled ovarian stimulation, and these oocytes were subjected to IVM before or after their vitrification. IVM was carried out in two commercial culture media not specifically designed for maturation. MII oocytes were then activated and embryo development until day 6 was evaluated. According to the results, a higher percentage of oocytes reach the MII stage if they are vitrified before they undergo IVM. Nevertheless, the medium used and the sample size determine whether these differences become significant or not. Similar survival rates and development to blastocysts were observed in all the conditions studied. | es_ES |
dc.description.sponsorship | This research was funded by the Human Fertility Chair of the University of Alicante and the Department of Biotechnology of the University of Alicante (VIGROB-186). | es_ES |
dc.language | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). | es_ES |
dc.subject | Germinal vesicle oocyte | es_ES |
dc.subject | In vitro maturation | es_ES |
dc.subject | Cryopreservation | es_ES |
dc.subject | Embryo development | es_ES |
dc.subject | Vitrification | es_ES |
dc.subject | Survival | es_ES |
dc.title | Potential Development of Vitrified Immature Human Oocytes: Influence of the Culture Medium and the Timing of Vitrification | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.peerreviewed | si | es_ES |
dc.identifier.doi | 10.3390/ijms24010417 | - |
dc.relation.publisherversion | https://doi.org/10.3390/ijms24010417 | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
Aparece en las colecciones: | INV - Grupo de Inmunología - Artículos de Revistas |
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