Effective Method for a Graphene Oxide with Impressive Selectivity in Carboxyl Groups
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Título: | Effective Method for a Graphene Oxide with Impressive Selectivity in Carboxyl Groups |
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Autor/es: | Rodríguez Pastor, Iluminada | López-Pérez, Adelia | Romero Sánchez, María Dolores | Pérez, Juana M. | Fernández, Ignacio | Martin-Gullon, Ignacio |
Grupo/s de investigación o GITE: | Residuos, Energía, Medio Ambiente y Nanotecnología (REMAN) |
Centro, Departamento o Servicio: | Universidad de Alicante. Departamento de Ingeniería Química | Universidad de Alicante. Instituto Universitario de Ingeniería de los Procesos Químicos |
Palabras clave: | Reduced graphene oxide | Graphite intercalated compound | Carboxyl groups | Bioconjugation |
Fecha de publicación: | 8-sep-2022 |
Editor: | MDPI |
Cita bibliográfica: | Rodríguez-Pastor I, López-Pérez A, Romero-Sánchez MD, Pérez JM, Fernández I, Martin-Gullon I. Effective Method for a Graphene Oxide with Impressive Selectivity in Carboxyl Groups. Nanomaterials. 2022; 12(18):3112. https://doi.org/10.3390/nano12183112 |
Resumen: | The development of new applications of graphene oxide in the biomedical field requires the covalent bonding of bioactive molecules to a sheet skeleton. Obtaining a large carboxyl group population over the surface is one of the main targets, as carboxyl group concentration in conventional graphene oxide is low among a majority of non-useful sp3-C-based functionalities. In the present work, we propose a selective method that yields an impressive increase in carboxyl group population using single-layer, thermally reduced graphene oxide as a precursor in a conventional Hummers–Offemann reaction. When starting with a reduced graphene oxide with no interlayer registry, sulfuric acid cannot form a graphite intercalated compound. Then, potassium permanganate attacks in in-plane (vacancies or holes) structural defects, which are numerous over a thermally reduced graphene oxide, as well as in edges, yielding majorly carboxyl groups without sheet cutting and unzipping, as no carbon dot formation was observed. A single-layer precursor with no ordered stacking prevents the formation of an intercalated compound, and it is this mechanism of the potassium permanganate that results in carboxyl group formation and the hydrophilic character of the compound. |
Patrocinador/es: | This research was funded by IVACE (project CREATEC-CV (IMCBTA/2019/40), Universidad de Alicante (UAIND21-07B), Gobierno de España (grant MCIN/AEI/10.13039/501100011033/Unión Europea “Next GenerationEU”/PRTR (programs PDC2021-121248-I00 and PLEC2021-007774, including the European Regional Development Fund—ERDF), Junta de Andalucía (project 102C2000004, CV20-78799, P20_01041 and UAL-FEDER UAL2020-AGR-B1781) and Universidad de Almería (Hipatia grant for. J.M.P.) |
URI: | http://hdl.handle.net/10045/127974 |
ISSN: | 2079-4991 |
DOI: | 10.3390/nano12183112 |
Idioma: | eng |
Tipo: | info:eu-repo/semantics/article |
Derechos: | © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
Revisión científica: | si |
Versión del editor: | https://doi.org/10.3390/nano12183112 |
Aparece en las colecciones: | INV - REMAN - Artículos de Revistas |
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