Characterization of Dysfunctional Lens Index and Opacity Grade in a Healthy Population
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Título: | Characterization of Dysfunctional Lens Index and Opacity Grade in a Healthy Population |
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Autor/es: | Martínez-Plaza, Elena | Ruiz Fortes, Pedro | Soto-Negro, Roberto | Hernández Rodríguez, Carlos Javier | Molina-Martín, Ainhoa | Arias-Puente, Alfonso | Piñero, David P. |
Grupo/s de investigación o GITE: | Grupo de Óptica y Percepción Visual (GOPV) |
Centro, Departamento o Servicio: | Universidad de Alicante. Departamento de Óptica, Farmacología y Anatomía |
Palabras clave: | Dysfunctional lens syndrome | Cataract | Dysfunctional lens index | High-order aberrations |
Área/s de conocimiento: | Óptica |
Fecha de publicación: | 7-may-2022 |
Editor: | MDPI |
Cita bibliográfica: | Martínez-Plaza E, Ruiz-Fortes P, Soto-Negro R, Hernández-Rodríguez CJ, Molina-Martín A, Arias-Puente A, Piñero DP. Characterization of Dysfunctional Lens Index and Opacity Grade in a Healthy Population. Diagnostics. 2022; 12(5):1167. https://doi.org/10.3390/diagnostics12051167 |
Resumen: | This study enrolled 61 volunteers (102 eyes) classified into subjects < 50 years (group 1) and subjects ≥ 50 years (group 2). Dysfunctional Lens Index (DLI); opacity grade; pupil diameter; and corneal, internal, and ocular higher order aberrations (HOAs) were measured with the i-Trace system (Tracey Technologies). Mean DLI was 8.89 ± 2.00 and 6.71 ± 2.97 in groups 1 and 2, respectively, being significantly higher in group 1 in all and right eyes (both p < 0.001). DLI correlated significantly with age (Rho = −0.41, p < 0.001) and pupil diameter (Rho = 0.20, p = 0.043) for all eyes, and numerous internal and ocular root-mean square HOAs for right, left, and all eyes (Rho ≤ −0.25, p ≤ 0.001). Mean opacity grade was 1.21 ± 0.63 and 1.48 ± 1.15 in groups 1 and 2, respectively, with no significant differences between groups (p ≥ 0.29). Opacity grade significantly correlated with pupil diameter for right and all eyes (Rho ≤ 0.33, p ≤ 0.013), and with some ocular root-mean square HOAs for right and all eyes (Rho ≥ 0.23, p ≤ 0.020). DLI correlates with age and might be used complementary to other diagnostic measurements for assessing the dysfunctional lens syndrome. Both DLI and opacity grade maintain a relationship with pupil diameter and internal and ocular HOAs, supporting that the algorithms used by the device may be based, in part, on these parameters. |
Patrocinador/es: | This research was funded by European Union-NextGenerationEU (E.M.-P.) and by the Ministry of Economy, Industry and Competitiveness of Spain within the program Ramón y Cajal, RYC-2016-20471 (D.P.P.). |
URI: | http://hdl.handle.net/10045/123448 |
ISSN: | 2075-4418 |
DOI: | 10.3390/diagnostics12051167 |
Idioma: | eng |
Tipo: | info:eu-repo/semantics/article |
Derechos: | © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
Revisión científica: | si |
Versión del editor: | https://doi.org/10.3390/diagnostics12051167 |
Aparece en las colecciones: | INV - GOPV - Artículos de Revistas |
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