Lledó, David, Grindlay, Guillermo, Sansano, Jose M.
1,3‐Dipolar Cycloadditions of Stabilized Azomethine Ylides and Electrophilic Alkenes Mediated by a Recyclable TSIL·AgOAc Catalyst
European Journal of Organic Chemistry. 2019, 25: 4095-4100. doi:10.1002/ejoc.201900724
URI: http://hdl.handle.net/10045/93808
DOI: 10.1002/ejoc.201900724
ISSN: 1434-193X (Print)
Abstract: 
The synthesis of a task‐specific ionic liquid (TSIL) based on a BMIM ionic liquid phosphane is achieved by modification of the original procedure. It is used as a ligand with AgOAc, and the resulting complex is fully characterized. This catalytic system promotes the 1,3‐dipolar cycloaddition of stabilized azomethine ylides and electrophilic alkenes using a green methodology. The green character was analyzed using an overall set of parameters finding the optimal conditions and individualized separation/purification methods for each cycloadduct. The determination of the most important green metrics is reported in this survey, demonstrating the value of this methodology on a laboratory scale or even at an industrial level.
Keywords:Cycloaddition, Green chemistry, Ionic liquids, Silver, Ylides
Wiley-VCH Verlag GmbH & Co. KGaA
info:eu-repo/semantics/article