Abellán-Llobregat, Alejandra, Jeerapan, Itthipon, Bandodkar, Amay, Vidal, Lorena, Canals, Antonio, Wang, Joe, Morallon, Emilia
A stretchable and screen-printed electrochemical sensor for glucose determination in human perspiration
Biosensors and Bioelectronics. 2017, 91: 885-891. doi:10.1016/j.bios.2017.01.058
URI: http://hdl.handle.net/10045/65156
DOI: 10.1016/j.bios.2017.01.058
ISSN: 0956-5663 (Print)
Abstract: 
Here we present two types of all-printable, highly stretchable, and inexpensive devices based on platinum (Pt)-decorated graphite for glucose determination in physiological fluids. Said devices are: a non-enzymatic sensor and an enzymatic biosensor, the latter showing promising results. Glucose has been quantified by measuring hydrogen peroxide (H2O2) reduction by chronoamperometry at −0.35 V (vs pseudo-Ag/AgCl) using glucose oxidase immobilized on Pt-decorated graphite. The sensor performs well for the quantification of glucose in phosphate buffer solution (0.25 M PBS, pH 7.0), with a linear range between 0 mM and 0.9 mM, high sensitivity and selectivity, and a low limit of detection (LOD). Thus, it provides an alternative non-invasive and on-body quantification of glucose levels in human perspiration. This biosensor has been successfully applied on real human perspiration samples and results also show a significant correlation between glucose concentration in perspiration and glucose concentration in blood measured by a commercial glucose meter.
Keywords:Glucose biosensor, Printed electronics, Stretchable device, H2O2, Catalyst, Perspiration
Elsevier
info:eu-repo/semantics/article