Alonso, Francisco, Rodríguez Fernández, María del Carmen, Sánchez Terrés, Daniel, Yus, Miguel
Ultrasound-promoted formation of isopentenyl alcohol dianion: straightforward synthesis of perhydrofuro (2,3-b)furans
ALONSO VALDÉS, Francisco, et al. "Ultrasound-promoted formation of isopentenyl alcohol dianion: straightforward synthesis of perhydrofuro (2,3-b)furans". Synthesis. No. 17 (2010). ISSN 0256-7245, pp. 3013-3020
URI: http://hdl.handle.net/10045/14660
DOI: 10.1055/s-0030-1258168
ISSN: 0256-7245
Abstract: 
Ultrasound has been found to accelerate the formation of isopentenyl alcohol dianion by metalation with butyllithium in diethyl ether-tetrahydrofuran. The reaction of this dianion with carbonyl compounds followed by intramolecular acetalization under Wacker-type conditions provides a direct route for the synthesis of 2-substituted perhydrofuro[2,3-b]furans.
Keywords:Metalation, Ultrasound, Polyanions, Wacker-type reaction, Cyclization, Perhydrofuro[2,3-b]furans
Georg Thieme Verlag
info:eu-repo/semantics/article