Algorithm for Correcting the Keratometric Error in the Estimation of the Corneal Power in Keratoconus Eyes after Accelerated Corneal Collagen Crosslinking

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Title: Algorithm for Correcting the Keratometric Error in the Estimation of the Corneal Power in Keratoconus Eyes after Accelerated Corneal Collagen Crosslinking
Authors: Piñero, David P. | Camps, Vicente J. | Caravaca Arens, Esteban | Fez Saiz, Dolores de | Blanes Mompó, Francisco J.
Research Group/s: Grupo de Óptica y Percepción Visual (GOPV)
Center, Department or Service: Universidad de Alicante. Departamento de Óptica, Farmacología y Anatomía
Keywords: Keratometric error | Corneal power calculation | Keratoconus eyes | Accelerated corneal collagen crosslinking
Knowledge Area: Óptica
Issue Date: 22-Oct-2017
Publisher: Hindawi Publishing Corporation
Citation: Journal of Ophthalmology. Volume 2017 (2017), Article ID 8529489, 8 pages. doi:10.1155/2017/8529489
Abstract: Purpose. To analyze the errors associated to corneal power calculation using the keratometric approach in keratoconus eyes after accelerated corneal collagen crosslinking (CXL) surgery and to obtain a model for the estimation of an adjusted corneal refractive index (nkadj) minimizing such errors. Methods. Potential differences (ΔPc) among keratometric (Pk) and Gaussian corneal power (PGauss c ) were simulated. Three algorithms based on the use of nkadj for the estimation of an adjusted keratometric corneal power (Pkadj) were developed. The agreement between Pk(1.3375) (keratometric power using the keratometric index of 1.3375), PGauss c , and Pkadj was evaluated. The validity of the algorithm developed was investigated in 21 keratoconus eyes undergoing accelerated CXL. Results. Pk(1.3375) overestimated corneal power between 0.3 and 3.2D in theoretical simulations and between 0.8 and 2.9D in the clinical study (ΔPc). Three linear equations were defined for nkadj to be used for different ranges of r1c. In the clinical study, differences between Pkadj and PGauss c did not exceed ±0.8D nk = 1.3375. No statistically significant differences were found between Pkadj and PGauss c (p > 0 05) and Pk(1.3375) and Pkadj (p < 0 001). Conclusions. The use of the keratometric approach in keratoconus eyes after accelerated CXL can lead to significant clinical errors. These errors can be minimized with an adjusted keratometric approach.
URI: http://hdl.handle.net/10045/70330
ISSN: 2090-004X (Print) | 2090-0058 (Online)
DOI: 10.1155/2017/8529489
Language: eng
Type: info:eu-repo/semantics/article
Rights: © 2017 David P. Piñero et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Peer Review: si
Publisher version: http://dx.doi.org/10.1155/2017/8529489
Appears in Collections:INV - GOPV - Artículos de Revistas

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