Aqueous Enantioselective Aldol Reaction of Methyl- and Phenylglyoxal Organocatalyzed by N-Tosyl-(S a)-binam-l-prolinamide

Navarro Moles, Fernando Javier; Guillena, Gabriela; Nájera, Carmen

Aqueous Enantioselective Aldol Reaction of Methyl- and Phenylglyoxal Organocatalyzed by N-Tosyl-(S a)-binam-l-prolinamide

Please use this identifier to cite or link to this item: http://hdl.handle.net/10045/45430

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DC Field	Value	Language
dc.contributor	Catálisis Estereoselectiva en Síntesis Orgánica (CESO)	es
dc.contributor	Síntesis Asimétrica (SINTAS)	es
dc.contributor.author	Navarro Moles, Fernando Javier	-
dc.contributor.author	Guillena, Gabriela	-
dc.contributor.author	Nájera, Carmen	-
dc.contributor.other	Universidad de Alicante. Departamento de Química Orgánica	es
dc.contributor.other	Universidad de Alicante. Instituto Universitario de Síntesis Orgánica	es
dc.date.accessioned	2015-03-03T10:09:29Z	-
dc.date.available	2015-03-03T10:09:29Z	-
dc.date.issued	2015-01-20	-
dc.identifier.citation	Synlett. 2015, 26(5): 656-660. doi:10.1055/s-0034-1379969	es
dc.identifier.issn	0936-5214 (Print)	-
dc.identifier.issn	1437-2096 (Online)	-
dc.identifier.uri	http://hdl.handle.net/10045/45430	-
dc.description.abstract	The direct aldol reaction between methylglyoxal (40% aqueous solution) or phenylglyoxal monohydrate and ketones or aldehydes is catalyzed by N-tosyl-(S a)-binam-l-prolinamide to afford the corresponding chiral γ-oxo-β-hydroxy carbonyl compounds, mainly as anti isomers with enantioselectivities up to 97%.	es
dc.description.sponsorship	This work was financially supported by the Ministerio de Economia y Competitividad (MINECO: Projects: CTQ2010-20387 and Consolider INGENIO CSD2007-0006), FEDER, the Generalitat Valenciana (Prometeo/2009/039), the University of Alicante and the EU (ORCA action CM0905).	es
dc.language	eng	es
dc.publisher	Georg Thieme Verlag	es
dc.rights	© Georg Thieme Verlag Stuttgart New York. http://www.thieme-connect.com/ejournals/toc/synlett	es
dc.subject	Methylglyoxal	es
dc.subject	Organocatalysis	es
dc.subject	Aldol	es
dc.subject	Prolinamide	es
dc.subject	Aqueous conditions	es
dc.subject.other	Química Orgánica	es
dc.title	Aqueous Enantioselective Aldol Reaction of Methyl- and Phenylglyoxal Organocatalyzed by N-Tosyl-(S a)-binam-l-prolinamide	es
dc.type	info:eu-repo/semantics/article	es
dc.peerreviewed	si	es
dc.identifier.doi	10.1055/s-0034-1379969	-
dc.relation.publisherversion	http://dx.doi.org/10.1055/s-0034-1379969	es
dc.identifier.cvID	A7693926	-
dc.rights.accessRights	info:eu-repo/semantics/openAccess	es
Appears in Collections:	INV - CESO - Artículos de Revistas INV - SINTAS - Artículos de Revistas

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