Mathematical modelling of the lower urinary tract

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Title: Mathematical modelling of the lower urinary tract
Authors: Soriano Payá, Antonio | Ruiz-Fernandez, Daniel | Gil, David | García-Chamizo, Juan Manuel | Maciá Pérez, Francisco
Research Group/s: Ingeniería Bioinspirada e Informática para la Salud | Lucentia | GrupoM. Redes y Middleware | Informática Industrial y Redes de Computadores
Center, Department or Service: Universidad de Alicante. Departamento de Tecnología Informática y Computación
Keywords: Lower urinary tract | Modelling | Simulation | Urodynamic
Knowledge Area: Arquitectura y Tecnología de Computadores
Issue Date: Mar-2013
Publisher: Elsevier
Citation: Computer Methods and Programs in Biomedicine. 2013, 109(3): 323-338. doi:10.1016/j.cmpb.2012.09.005
Abstract: The lower urinary tract is one of the most complex biological systems of the human body as it involved hydrodynamic properties of urine and muscle. Moreover, its complexity is increased to be managed by voluntary and involuntary neural systems. In this paper, a mathematical model of the lower urinary tract it is proposed as a preliminary study to better understand its functioning. Furthermore, another goal of that mathematical model proposal is to provide a basis for developing artificial control systems. Lower urinary tract is comprised of two interacting systems: the mechanical system and the neural regulator. The latter has the function of controlling the mechanical system to perform the voiding process. The results of the tests reproduce experimental data with high degree of accuracy. Also, these results indicate that simulations not only with healthy patients but also of patients with dysfunctions with neurological etiology present urodynamic curves very similar to those obtained in clinical studies.
Sponsor: This study has been supported as part of the research projects: Cooperative diagnosis system applied to urological dysfunctions (GV05/158) funded by the Government of Valencia (Spain); Ambulatory wireless system for prevention of female urinary incontinence (CIT-300100-2005-7) funded by the Spanish Ministry of Science.
ISSN: 0169-2607 (Print) | 1872-7565 (Online)
DOI: 10.1016/j.cmpb.2012.09.005
Language: eng
Type: info:eu-repo/semantics/article
Peer Review: si
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