PSA response to lenalidomide therapy in a pre-treated patient with metastatic prostate cancer refractory to hormones and chemotherapy: a case report
Por favor, use este identificador para citar o enlazar este ítem:
http://hdl.handle.net/10045/34301
Título: | PSA response to lenalidomide therapy in a pre-treated patient with metastatic prostate cancer refractory to hormones and chemotherapy: a case report |
---|---|
Autor/es: | Gasent Blesa, Joan Manel | Peris Godoy, Miguel | Fonfría Esparcia, María | Blasco Mollá, Sara | Mancheño Magán, Balbino | Sempere Ortells, José Miguel | Sánchez, José Luis |
Grupo/s de investigación o GITE: | Grupo de Inmunología |
Centro, Departamento o Servicio: | Universidad de Alicante. Departamento de Biotecnología |
Palabras clave: | Hormone-resistant prostate cancer | Prostate serum antigen | Lenalidomide |
Área/s de conocimiento: | Inmunología |
Fecha de publicación: | 18-abr-2012 |
Editor: | S. Karger AG, Basel |
Cita bibliográfica: | Case Reports in Oncology. 2012, 5: 181-186. doi:10.1159/000336481 |
Resumen: | Hormone-resistant prostate cancer (HRPC) occurs when prostate cancer is no longer responsive to hormone therapy. Treatment options are limited, and there is a clear necessity for therapies that improve outcome. Preclinical and clinical evidence supports the role of the immunomodulatory agent lenalidomide in HRPC. In this paper, we report that lenalidomide showed antitumoral activity in a patient with HRPC and bone metastases pre-treated with chemotherapy, decreased the PSA level and improved the patient’s health status for the first 5 months. It is important to emphasize that it was not associated with hematologic toxicity. |
URI: | http://hdl.handle.net/10045/34301 |
ISSN: | 1662-6575 |
DOI: | 10.1159/000336481 |
Idioma: | eng |
Tipo: | info:eu-repo/semantics/article |
Derechos: | © 2012 S. Karger AG, Basel. This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License (www.karger.com/OA-license), applicable to the online version of the article only. Distribution for non-commercial purposes only. |
Revisión científica: | si |
Versión del editor: | http://dx.doi.org/10.1159/000336481 |
Aparece en las colecciones: | INV - Grupo de Inmunología - Artículos de Revistas |
Archivos en este ítem:
Archivo | Descripción | Tamaño | Formato | |
---|---|---|---|---|
2012_Gasent_etal_CaseRepOncol.pdf | 557,58 kB | Adobe PDF | Abrir Vista previa | |
Este ítem está licenciado bajo Licencia Creative Commons