Acute lymphoblastic leukaemia among Spanish children and mothers' occupation: a case-control study

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Title: Acute lymphoblastic leukaemia among Spanish children and mothers' occupation: a case-control study
Authors: Infante-Rivard, Claire | Mur, Patricia | Armstrong, Ben | Álvarez-Dardet, Carlos | Bolúmar Montrull, Francisco
Research Group/s: Salud Pública
Center, Department or Service: Universidad de Alicante. Departamento de Enfermería Comunitaria, Medicina Preventiva y Salud Pública e Historia de la Ciencia
Keywords: Acute lymphoblastic leukaemia | Case-control study | Pregnancy
Knowledge Area: Medicina Preventiva y Salud Pública
Issue Date: Mar-1991
Publisher: BMJ Publishing Group
Citation: INFANTE-RIVARD, Claire, et al. "Acute lymphoblastic leukaemia among Spanish children and mothers' occupation: a case-control study". Journal of Epidemiology and Community Health. Vol. 45, No. 1 (March 1991). ISSN 0143-005X, pp. 11-15
Abstract: STUDY OBJECTIVE: The aim was to investigate the association between mothers' occupational exposure during pregnancy and the incidence of acute lymphoblastic leukaemia in children. DESIGN: The study was a case-control investigation. A face to face interview was used to assess exposures at work and relevant confounding variables. SETTING: The study was community based and was carried out in five provinces of Spain. SUBJECTS: 128 cases less than 15 years of age were interviewed (91% of those eligible). Controls (one for each case) were chosen from the census lists and were matched on year of birth, sex and municipality. MEASUREMENTS AND MAIN RESULTS: Children of mothers working at home had a relative risk (RR) of 7.0 (95% CI = 1.59-30.79) of developing acute lymphoblastic leukaemia. Exposure to organic dust was associated with a RR of 5.5 (95% CI = 1.21-24.8). There was a statistically significant interaction between exposure to organic dust and working at home. The majority of women working at home were hired by local industries to sew different types of tissues (cotton, wool, synthetic fibres) on a machine. CONCLUSION: A similar association has not been reported before: if confirmed, this finding may suggest a new health concern.
ISSN: 0143-005X
DOI: 10.1136/jech.45.1.11
Language: eng
Type: info:eu-repo/semantics/article
Rights: Journal of Epidemiology & Community Health.
Peer Review: si
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Appears in Collections:INV - SP - Artículos de Revistas
Institucional - IUIEG - Publicaciones

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