MicroRNAs in the Mouse Developing Retina

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dc.contributorNeurobiología del Sistema Visual y Terapia de Enfermedades Neurodegenerativas (NEUROVIS)es_ES
dc.contributor.authorNavarro-Calvo, Jorge-
dc.contributor.authorEsquiva, Gema-
dc.contributor.authorGómez-Vicente, Violeta-
dc.contributor.authorValor, Luis M.-
dc.contributor.otherUniversidad de Alicante. Departamento de Óptica, Farmacología y Anatomíaes_ES
dc.date.accessioned2023-03-08T09:24:33Z-
dc.date.available2023-03-08T09:24:33Z-
dc.date.issued2023-02-03-
dc.identifier.citationNavarro-Calvo J, Esquiva G, Gómez-Vicente V, Valor LM. MicroRNAs in the Mouse Developing Retina. International Journal of Molecular Sciences. 2023; 24(3):2992. https://doi.org/10.3390/ijms24032992es_ES
dc.identifier.issn1422-0067-
dc.identifier.urihttp://hdl.handle.net/10045/132665-
dc.description.abstractThe retina is among the highest organized tissues of the central nervous system. To achieve such organization, a finely tuned regulation of developmental processes is required to form the retinal layers that contain the specialized neurons and supporting glial cells to allow precise phototransduction. MicroRNAs are a class of small RNAs with undoubtful roles in fundamental biological processes, including neurodevelopment of the brain and the retina. This review provides a short overview of the most important findings regarding microRNAs in the regulation of retinal development, from the developmental-dependent rearrangement of the microRNA expression program to the key roles of particular microRNAs in the differentiation and maintenance of retinal cell subtypes.es_ES
dc.description.sponsorshipThis research was funded by Programa Estatal de Generación de Conocimiento y Fortalecimiento del Sistema Español de I + D + i financed by Instituto de Salud Carlos III and Fondo Europeo de Desarrollo Regional 2014–2020 (grant PI19/00125), Ayudas para el Apoyo y Fomento de la Investigación financed by ISABIAL (grant 2021-0406), and Ayudas para proyectos emergentes de la GVA (GV/2020/064). L.M.V. is the recipient of a Miguel Servet II contract (CPII20/00025), financed by Instituto de Salud Carlos III and Fondo Social Europeo 2014–2020, Programa Estatal de Promoción del Talento y su empleabilidad en I + D + i.es_ES
dc.languageenges_ES
dc.publisherMDPIes_ES
dc.rights© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).es_ES
dc.subjectRetinaes_ES
dc.subjectMousees_ES
dc.subjectDiceres_ES
dc.subjectmiR-183/96/182es_ES
dc.subjectmiR-204/211es_ES
dc.subjectmiR-124es_ES
dc.subjectmiR-9es_ES
dc.subjectlet-7es_ES
dc.subjectTranscriptomicses_ES
dc.titleMicroRNAs in the Mouse Developing Retinaes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.peerreviewedsies_ES
dc.identifier.doi10.3390/ijms24032992-
dc.relation.publisherversionhttps://doi.org/10.3390/ijms24032992es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII//PI19%2F00125es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ISCIII//CPII20%2F00025es_ES
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