Controlled Release, Disintegration, Antioxidant, and Antimicrobial Properties of Poly (Lactic Acid)/Thymol/Nanoclay Composites

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Title: Controlled Release, Disintegration, Antioxidant, and Antimicrobial Properties of Poly (Lactic Acid)/Thymol/Nanoclay Composites
Authors: Ramos, Marina | Fortunati, Elena | Beltrán Sanahuja, Ana | Peltzer, Mercedes Ana | Cristofaro, Francesco | Visai, Livia | Valente, Artur J.M. | Jiménez, Alfonso | Kenny, José María | Garrigós, María del Carmen
Research Group/s: Análisis de Polímeros y Nanomateriales
Center, Department or Service: Universidad de Alicante. Departamento de Química Analítica, Nutrición y Bromatología
Keywords: PLA | Nanocomposites | Functional properties | Thymol | Migration | Films
Knowledge Area: Química Analítica
Issue Date: 20-Aug-2020
Publisher: MDPI
Citation: Ramos M, Fortunati E, Beltrán A, Peltzer M, Cristofaro F, Visai L, Valente AJ, Jiménez A, Kenny JM, Garrigós MC. Controlled Release, Disintegration, Antioxidant, and Antimicrobial Properties of Poly (Lactic Acid)/Thymol/Nanoclay Composites. Polymers. 2020; 12(9):1878. https://doi.org/10.3390/polym12091878
Abstract: Nano-biocomposite films based on poly (lactic acid) (PLA) were prepared by adding thymol (8 wt.%) and a commercial montmorillonite (D43B) at different concentrations (2.5 and 5 wt.%). The antioxidant, antimicrobial, and disintegration properties of all films were determined. A kinetic study was carried out to evaluate the thymol release from the polymer matrix into ethanol 10% (v/v) as food simulant. The nanostructured networks formed in binary and ternary systems were of interest in controlling the release of thymol into the food simulant. The results indicated that the diffusion of thymol through the PLA matrix was influenced by the presence of the nanoclay. Disintegration tests demonstrated that the incorporation of both additives promoted the breakdown of the polymer matrix due to the presence of the reactive hydroxyl group in the thymol structure and ammonium groups in D43B. Active films containing thymol and D43B efficiently enhanced the antioxidant activity (inhibition values higher than 77%) of the nano-biocomposites. Finally, the addition of 8 wt.% thymol and 2.5 wt.% D43B significantly increased the antibacterial activity against Escherichia coli and Staphylococcus aureus 8325-4, resulting in a clear advantage to improve the shelf-life of perishable packaged food.
Sponsor: Authors would like to thank Spanish Ministry of Economy and Competitiveness (MAT2017-84909-C2-1-R) and Generalitat Valenciana (IDIFEDER/2018/007) for their support of this research. Marina Ramos would like to thank University of Alicante (Spain) for the UAFPU2011-48539721S predoctoral research grant. AJMV thanks ´Coimbra Chemistry Center and Fundação para a Ciência e Tecnologia (FCT) for the financial support through the programmes UID/QUI/UI0313/2020 and COMPETE.
URI: http://hdl.handle.net/10045/108659
ISSN: 2073-4360
DOI: 10.3390/polym12091878
Language: eng
Type: info:eu-repo/semantics/article
Rights: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Peer Review: si
Publisher version: https://doi.org/10.3390/polym12091878
Appears in Collections:INV - NANOBIOPOL - Artículos de Revistas

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