Systematic review of potential causes of intraocular lens opacification

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Título: Systematic review of potential causes of intraocular lens opacification
Autor/es: Fernández, Joaquín | Sánchez-García, Alicia | Rodríguez-Vallejo, Manuel | Piñero, David P.
Grupo/s de investigación o GITE: Grupo de Óptica y Percepción Visual (GOPV)
Centro, Departamento o Servicio: Universidad de Alicante. Departamento de Óptica, Farmacología y Anatomía
Palabras clave: Acrylic IOL | Cataract surgery | Intraocular lens | IOL explantation | IOL opacification
Área/s de conocimiento: Óptica
Fecha de publicación: 2020
Editor: Wiley
Cita bibliográfica: Clinical & Experimental Ophthalmology. 2020, 48(1): 89-97. doi:10.1111/ceo.13650
Resumen: Intraocular lens (IOL) opacification is an infrequent complication of cataract surgery. Surface analysis has demonstrated that the opacification of IOLs is related to calcium or phosphate precipitation on or within the lenses, but the associated mechanisms are unknown, and the scientific literature is heterogeneous and limited to case series and retrospective studies. The purpose of this systematic review was to analyse the most frequent conditions associated with opacification of IOLs reported by studies. A search was carried out using the PubMed MEDLINE, Web of Science and Scopus databases. The quality of the studies selected was evaluated using the Pierson tool. The search provided a total of 811 articles, of which 39 were selected following the inclusion and exclusion criteria. The most common opacified lenses were hydrophilic IOLs according to our analysis. The mean time of appearance of lens opacification was 14.93 ± 17.82 months. The most frequent conditions associated with opacification of the IOLs were Descemet Stripping with Automated Endothelial Keratoplasty (DSAEK/DSEK) and diabetes mellitus (DM), followed by pars plana vitrectomy (PPV), blood hypertension (HT), and glaucoma. Concerning the quality analysis, the mean score was 7.00 ± 1.43 (scoring range from 0 to 10), indicating an acceptable quality of the case reports and retrospective studies. In conclusion, DSAEK/DSEK, DM, PPV, glaucoma and hypertension are conditions with potential risk of IOL opacification after cataract surgery, especially when implanting hydrophilic acrylic IOLs.
Patrocinador/es: Ministry of Economy, Industry and Competitiveness of Spain, Grant/Award Number: RYC‐2016‐20471.
URI: http://hdl.handle.net/10045/102450
ISSN: 1442-6404 (Print) | 1442-9071 (Online)
DOI: 10.1111/ceo.13650
Idioma: eng
Tipo: info:eu-repo/semantics/article
Derechos: © 2019 Royal Australian and New Zealand College of Ophthalmologists
Revisión científica: si
Versión del editor: https://doi.org/10.1111/ceo.13650
Aparece en las colecciones:INV - GOPV - Artículos de Revistas

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