Fernández Ibáñez, María Ángeles, Maciá, Beatriz, Alonso, Diego A., Pastor, Isidro M.
Palladium and organocatalysis: an excellent recipe for asymmetric synthesis
Molecules. 2013, 18: 10108-10121. doi:10.3390/molecules180910108
URI: http://hdl.handle.net/10045/33642
DOI: 10.3390/molecules180910108
ISSN: 1420-3049 (Print)
Abstract: 
The dual activation of simple substrates by the combination of organocatalysis and palladium catalysis has been successfully applied in a variety of different asymmetric transformations. Thus, the asymmetric a-allylation of carbonyl compounds, a-fluorination of acyl derivatives, decarboxylative protonation of β-dicarbonyl compounds, cyclization reactions of alkynyl carbonyl compounds and β-functionalization of aldehydes have been efficiently achieved employing this double-catalytic methodology.
Keywords:Palladium, Organocatalysis, Asymmetric synthesis, Dual activation, Tandem reaction, Allylation, Fluorination, Decarboxylative protonation
MDPI
info:eu-repo/semantics/article