Mancebo Aracil, Juan, Martín Rodríguez, María, Nájera, Carmen, Sansano, Jose M., Costa, Paulo R.R., Lima, Evanoel Crizanto de, Dias, Ayres G.
Binap-silver salts as chiral-catalysts for the enantioselective 1,3-dipolar cycloaddition of azomethine ylides and alkenes
MANCEBO-ARACIL, Juan, et al. "Binap-silver salts as chiral-catalysts for the enantioselective 1,3-dipolar cycloaddition of azomethine ylides and alkenes". Tetrahedron: Asymmetry. Vol. 23, No. 22-23 (15 Dec. 2012). ISSN 0957-4166, pp. 1596-1606
URI: http://hdl.handle.net/10045/25420
DOI: 10.1016/j.tetasy.2012.10.015
ISSN: 0957-4166 (Print)
Abstract: 
Binap-AgSbF6 catalyzed 1,3-dipolar cycloadditions between azomethine ylides and electrophilic alkenes are described and compared with analogous transformations mediated by other Binap-silver(I) salt complexes. Maleimides and 1,2-bis(phenylsulfonyl)ethylene are suitable dipolarophiles for obtaining very good enantioselectivities, even better values are generated by a multicomponent version. There are some very interesting applications of the disulfonylated cycloadducts in the total synthesis of cis-2,5-disubstituted pyrrolidines, precursors of natural products, or valuable intermediates in the synthesis of antiviral compounds.
Keywords:Enantioselective, Azomethine
Elsevier
info:eu-repo/semantics/article