Alonso, Francisco, Moglie, Yanina, Radivoy, Gabriel, Yus, Miguel
Copper-catalysed multicomponent click synthesis of 5-alkynyl 1,2,3-triazoles under ambient conditions
ALONSO, Francisco, et al. "Copper-catalysed multicomponent click synthesis of 5-alkynyl 1,2,3-triazoles under ambient conditions". Synlett. Vol. 23, No. 15 (2012). ISSN 0936-5214, pp. 2179-2182
URI: http://hdl.handle.net/10045/24175
DOI: 10.1055/s-0031-1290445
ISSN: 0936-5214 (Print)
Abstract: 
Copper(I) oxide has been found to effectively catalyse the multicomponent click synthesis of fully substituted 5-alkynyl 1,2,3-triazoles from organic halides, sodium azide, and terminal ­alkynes in methanol under ambient conditions.
Keywords:Alkynes, Alkyl halides, Azides, Cycloaddition, Copper, Cross-coupling, Heterocycles, Multicomponent reaction
Georg Thieme Verlag
info:eu-repo/semantics/article