A scoring system to detect fixed airflow limitation in smokers from simple easy-to-use parameters

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Títol: A scoring system to detect fixed airflow limitation in smokers from simple easy-to-use parameters
Autors: Román-Conejos, Esther | Palazón Bru, Antonio | Folgado-de la Rosa, David M. | Sánchez-Molla, Manuel | Rizo-Baeza, Mercedes | Gil Guillén, Vicente | Cortés Castell, Ernesto
Grups d'investigació o GITE: Salud y Cuidados en Grupos Vulnerables (SACU)
Centre, Departament o Servei: Universidad de Alicante. Departamento de Enfermería
Paraules clau: Fixed airflow limitation | Smokers | Simple easy-to-use parameters
Àrees de coneixement: Enfermería
Data de publicació: 6-de setembre-2018
Editor: Springer Nature
Citació bibliogràfica: Scientific Reports. 2018, 8: 13329. doi:10.1038/s41598-018-31198-8
Resum: No validated screening method currently exists for Chronic Obstructive Pulmonary Disease (COPD) in smokers. Therefore, we constructed a predictive model with simple parameters that can be applied for COPD screening to detect fixed airflow limitation. This observational cross-sectional study included a random sample of 222 smokers with no previous diagnosis of COPD undertaken in a Spanish region in 2014–2016. The main variable was fixed airflow limitation by spirometry. The secondary variables (COPD factors) were: age, gender, smoking (pack-years and Fagerström test), body mass index, educational level, respiratory symptoms and exacerbations. A points system was developed to predict fixed airflow limitation based on secondary variables. The model was validated internally through bootstrapping, determining discrimination and calibration. The system was then integrated into a mobile application for Android. Fifty-seven patients (25.7%) presented fixed airflow limitation. The points system included as predictors: age, pack-years, Fagerström test and presence of respiratory symptoms. Internal validation of the system was very satisfactory, both in discrimination and calibration. In conclusion, a points system has been constructed to predict fixed airflow limitation in smokers with no previous COPD. This system can be integrated as a screening tool, though it should be externally validated in other geographical regions.
URI: http://hdl.handle.net/10045/79329
ISSN: 2045-2322
DOI: 10.1038/s41598-018-31198-8
Idioma: eng
Tipus: info:eu-repo/semantics/article
Drets: Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Revisió científica: si
Versió de l'editor: https://doi.org/10.1038/s41598-018-31198-8
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