Asymmetric Organocatalytic Electrophilic Heterofunctionalization of Oxindoles

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dc.contributorNuevos Materiales y Catalizadores (MATCAT)es_ES
dc.contributorCatálisis Estereoselectiva en Síntesis Orgánica (CESO)es_ES
dc.contributor.authorFreckleton, Megan-
dc.contributor.authorBaeza, Alejandro-
dc.contributor.authorBenavent, Llorenç-
dc.contributor.authorChinchilla, Rafael-
dc.contributor.otherUniversidad de Alicante. Departamento de Química Orgánicaes_ES
dc.contributor.otherUniversidad de Alicante. Instituto Universitario de Síntesis Orgánicaes_ES
dc.identifier.citationAsian Journal of Organic Chemistry. 2018, 7(6): 1006-1014. doi:10.1002/ajoc.201800146es_ES
dc.identifier.issn2193-5807 (Print)-
dc.identifier.issn2193-5815 (Online)-
dc.description.abstractThe asymmetric synthesis of 3‐substituted oxindoles is a topic of considerable importance because these functionalized heterocycles are found in many natural products and drugs. In the last decade, significant advances have been made towards the asymmetric synthesis of 3‐heteroatom‐substituted oxindoles as a result of major improvements in asymmetric organocatalysis. This review will focus on the different types of asymmetric electrophilic organocatalyzed reactions, including the amination, halogenation, hydroxylation, and sulfenylation of oxindoles to form their enantioenriched 3‐heterosubstituted derivatives.es_ES
dc.description.sponsorshipWe thank the Spanish Ministerio de Economía, Industria y Competitividad (CTQ2015-66624-P) and the University of Alicante (VIGROB-173, VIGROB-285, UAUSTI17-06, UADIF17-27) for the financial support. M.F. thanks the University of Edinburgh for an ERASMUS fellowship.es_ES
dc.publisherWiley-VCH Verlag GmbH & Co. KGaAes_ES
dc.rights© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheimes_ES
dc.subjectAsymmetric catalysises_ES
dc.subjectQuaternary stereocenterses_ES
dc.subject.otherQuímica Orgánicaes_ES
dc.titleAsymmetric Organocatalytic Electrophilic Heterofunctionalization of Oxindoleses_ES
Appears in Collections:INV - MATCAT - Artículos de Revistas
INV - CESO - Artículos de Revistas
INV - AMIC - Artículos de Revistas

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