Biscarboxy-Functionalized Imidazole and Palladium as Highly Active Catalytic System in Protic Solvents: Methanol and Water
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Title: | Biscarboxy-Functionalized Imidazole and Palladium as Highly Active Catalytic System in Protic Solvents: Methanol and Water |
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Authors: | Martínez Flores, Regina | Pastor, Isidro M. | Yus, Miguel |
Research Group/s: | Nuevos Materiales y Catalizadores (MATCAT) | Síntesis Asimétrica (SINTAS) |
Center, Department or Service: | Universidad de Alicante. Departamento de Química Orgánica | Universidad de Alicante. Instituto Universitario de Síntesis Orgánica |
Keywords: | Palladium | Organometallic reagents | Heterocycles | Solvent effects | Cross-coupling |
Knowledge Area: | Química Orgánica |
Issue Date: | 2014 |
Publisher: | Georg Thieme Verlag |
Citation: | Synthesis. 2014, 46(21): 2965-2975. doi:10.1055/s-0034-1378552 |
Abstract: | The coupling reaction between aryl bromides and boron reagents is efficiently catalyzed by an in situ generated palladium complex obtained from palladium(II) acetate (0.1 mol%) and 1,3-bis(carboxymethyl)imidazole (0.2 mol%). The catalytic system is very active in protic solvents, especially in methanol. Biaryl derivatives have been prepared in good isolated yields (up to >99%), and additionally styrene and stilbene derivatives have also been prepared by means of this protocol. |
Sponsor: | Financial support from the Ministerio de Ciencia e Innovación (MICINN) of Spain (Project Nos. CTQ2007-65218, CTQ2011-24165, Consolider Ingenio 2010 CSD2007-00006), the Generalitat Valenciana (PROMETEO/2009/039 and FEDER), and the Universidad de Alicante is acknowledged. |
URI: | http://hdl.handle.net/10045/46301 |
ISSN: | 0039-7881 (Print) | 1437-210X (Online) |
DOI: | 10.1055/s-0034-1378552 |
Language: | eng |
Type: | info:eu-repo/semantics/article |
Rights: | © Georg Thieme Verlag Stuttgart · New York |
Peer Review: | si |
Publisher version: | http://dx.doi.org/10.1055/s-0034-1378552 |
Appears in Collections: | INV - MATCAT - Artículos de Revistas INV - SINTAS - Artículos de Revistas INV - AMIC - Artículos de Revistas |
Files in This Item:
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2014_Martinez_etal_Synthesis_final.pdf | Versión final (acceso restringido) | 388,24 kB | Adobe PDF | Open Request a copy |
2014_Martinez_etal_Synthesis_rev.pdf | Versión revisada (acceso abierto) | 267,45 kB | Adobe PDF | Open Preview |
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