Microarray tools to unveil viral-microbe interactions in nature

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Título: Microarray tools to unveil viral-microbe interactions in nature
Autor/es: Santos Sánchez, Fernando | Martinez-Garcia, Manuel | Parro, Víctor | Anton, Josefa
Grupo/s de investigación o GITE: Ecología Microbiana Molecular
Centro, Departamento o Servicio: Universidad de Alicante. Departamento de Fisiología, Genética y Microbiología
Palabras clave: Phage-bacteria interactions | Microarray analysis | Virus ec | Microbiology | Virus- | Virus-host interaction
Área/s de conocimiento: Microbiología
Fecha de publicación: 7-jul-2014
Editor: Frontiers Media
Cita bibliográfica: Frontiers in Ecology and Evolution. 2014, 2:31. doi:10.3389/fevo.2014.00031
Resumen: The interactions between viruses and their microbial hosts play a central role in the control of microbial communities in nature. However, the study of such interactions within the uncultured majority is technically very challenging. Here, we review how microarray tools can be used to analyze the interactions between viruses and their microbial hosts in nature, away from laboratory pure culture-based models. We show examples of how DNA arrays have been used to study the expression of viral assemblages in natural samples, and to assign viruses to hosts within uncultured communities. Finally, we briefly discuss the possibilities of protein and glycan arrays to gain insight into the ways microbes interact with their viruses.
Patrocinador/es: Our current studies with viral microarrays are supported by projects CGL2012-39627-C03-01 (to Josefa Antón) and AYA2011-24803 (to Víctor Parro) of the Spanish Ministry of Science and Innovation, which are co-financed with FEDER support from the European Union.
URI: http://hdl.handle.net/10045/45255
ISSN: 2296-701X
DOI: 10.3389/fevo.2014.00031
Idioma: eng
Tipo: info:eu-repo/semantics/article
Derechos: © 2014 Santos, Martínez-García, Parro and Antón. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Revisión científica: si
Versión del editor: http://dx.doi.org/10.3389/fevo.2014.00031
Aparece en las colecciones:INV - EMM - Artículos de Revistas

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