Emotional distress and health-related quality of life in patients on hemodialysis: the clinical value of COOP-WONCA charts

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Title: Emotional distress and health-related quality of life in patients on hemodialysis: the clinical value of COOP-WONCA charts
Authors: Arenas Jiménez, María Dolores | Álvarez-Ude Cotera, Fernando | Reig-Ferrer, Abilio | Zito, Juan Pablo | Gil González, María Teresa | Carretón, María Antonia | Albiach, Begoña | Moledous, Analía
Research Group/s: Calidad de Vida, Bienestar Psicológico y Salud
Center, Department or Service: Universidad de Alicante. Departamento de Psicología de la Salud | Hospital Perpetuo Socorro (Alicante) | Hospital General de Segovia
Keywords: Anxiety | Depression | Hemodialysis | Health-related quality of life | COOP-WOCA charts
Knowledge Area: Personalidad, Evaluación y Tratamiento Psicológico
Issue Date: Jun-2007
Publisher: Wichtig
Citation: ARENAS JIMÉNEZ, María Dolores, et al. "Emotional distress and health-related quality of life in patients on hemodialysis: the clinical value of COOP-WONCA charts". Journal of Nephrology. Vol. 20, No. 3 (May-June 2007). ISSN 1121-8428, pp. 304-310
Abstract: Background: A significant percentage of patients on hemodialysis (HD) present with affective disorders such as anxiety and/or depression. The purpose of this study was to explore adaptive mixed affective disorders of patients on HD and to analyze the clinical value of a brief health-related quality-of-life (HRQoL) instrument, the COOP-WONCA charts, in our population of HD patient. Methods: Seventy-five patients (mean age 49.2 years; range 20.1-64.9), who had been on HD for a mean 110 months (range 6.1-364.5 months) were studied. The Beck Depression Inventory (BDI), Hamilton Scale of Depression (HDRS) and Hamilton Scale of Anxiety (HARS) were used. To evaluate patient HRQoL, we used the validated Spanish version of the COOPWONCA charts. Results: Of the 75 patients studied, 44.0% (BDI) and 53.4% (HDRS) had some depressive symptoms which were moderatesevere in 14.7% (BDI) and in 22.7% (HDRS). Anxiety symptoms were observed in 46.6% of the patients (13.3% were of moderate- severe degree). There was a high level of association between both depression scales (BDI and HDRS) (r=0.70; p<0.001), as well as between both scales and the HARS (HDRS, r=0.82; p<0.001; BDI, r=0.53; p<0.001). The most affected dimensions of the COOP-WONCA charts were “Physical fitness” and “Overall health,” whereas the least affected were “Social activities” and “Daily activities.” The global score of the COOP-WONCA charts was associated with the presence of depressive (BDI, r=0.64, and HDRS, r=0.75; p<0.001) and anxiety symptoms (HARS, r=0.52; p<0.001). A score of ≥3 corresponding to the dimension “Feelings” on the COOP-WONCA charts allowed the detection of 81.8% of the patients with clinically significant depressive symptoms (BDI >18), with a sensitivity of 96.8% and a specificity of 75% for this cutoff point. Conclusions: A high percentage of patients on HD present with mixed emotional disorders (anxiety and/or depression); a good correlation is observed between HRQoL and the levels of anxiety and depression in these patients; and measuring HRQoL with the COOP-WONCA charts may help diagnose such problems.
URI: http://hdl.handle.net/10045/4226
ISSN: 1121-8428 | 1724-6059
Language: eng
Type: info:eu-repo/semantics/article
Rights: © Società Italiana di Nefrologia
Peer Review: si
Appears in Collections:INV - CV, BP Y S - Artículos de Revistas

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