Chiral β-amino alcohols as ligands for the ruthenium-catalyzed asymmetric transfer hydrogenation of N-phosphinyl ketimines
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Campo DC | Valor | Idioma |
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dc.contributor | Síntesis Asimétrica (SINTAS) | es |
dc.contributor | Catálisis Estereoselectiva en Síntesis Orgánica (CESO) | es |
dc.contributor.author | Pablo, Óscar | - |
dc.contributor.author | Guijarro, David | - |
dc.contributor.author | Yus, Miguel | - |
dc.contributor.other | Universidad de Alicante. Departamento de Química Orgánica | es |
dc.date.accessioned | 2013-12-04T09:17:05Z | - |
dc.date.available | 2013-12-04T09:17:05Z | - |
dc.date.issued | 2012-01-09 | - |
dc.identifier.citation | Applied Sciences. 2012, 2(1): 1-12. doi:10.3390/app2010001 | es |
dc.identifier.issn | 2076-3417 | - |
dc.identifier.uri | http://hdl.handle.net/10045/34358 | - |
dc.description.abstract | Some chiral β-amino alcohols have been evaluated as potential ligands for the ruthenium-catalyzed asymmetric transfer hydrogenation (ATH) of N-phosphinyl ketimines in isopropyl alcohol. The ruthenium complex prepared from [RuCl2(p-cymene)]2 and (1S,2R)-1-amino-2-indanol has shown to be an efficient catalyst for the ATH of several N-(diphenylphosphinyl)imines, affording the reduction products in very good isolated yields and enantiomeric excesses up to 82%. The inherent rigidity of the indane ring system present in the ligand seems to be very important to achieve good enantioselectivities. | es |
dc.description.sponsorship | This work was generously supported by the Spanish Ministerio de Ciencia e Innovación (MICINN; Grant No. CONSOLIDER INGENIO 2010, CSD2007-00006, CTQ2007-65218, and CTQ11-24151) and the Generalitat Valenciana (PROMETEO/2009/039 and FEDER). Óscar Pablo thanks the Spanish Ministerio de Educación for a predoctoral fellowship (Grant No. AP2008-00989). | es |
dc.language | eng | es |
dc.publisher | MDPI | es |
dc.rights | © 2012 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). | es |
dc.subject | N-(diphenylphosphinyl)imine | es |
dc.subject | Asymmetric transfer hydrogenation | es |
dc.subject | Ruthenium catalyst | es |
dc.subject | β-amino alcohol | es |
dc.subject | Isopropyl alcohol | es |
dc.subject.other | Química Orgánica | es |
dc.title | Chiral β-amino alcohols as ligands for the ruthenium-catalyzed asymmetric transfer hydrogenation of N-phosphinyl ketimines | es |
dc.type | info:eu-repo/semantics/article | es |
dc.peerreviewed | si | es |
dc.identifier.doi | 10.3390/app2010001 | - |
dc.relation.publisherversion | http://dx.doi.org/10.3390/app2010001 | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
Aparece en las colecciones: | INV - CESO - Artículos de Revistas INV - SINTAS - Artículos de Revistas |
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