The ordinary light microscope: an appropriate tool for provisional detection and identification of crystals in synovial fluid

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Title: The ordinary light microscope: an appropriate tool for provisional detection and identification of crystals in synovial fluid
Authors: Pascual, Eliseo | Tovar, Juan | Ruiz-Cantero, María Teresa
Research Group/s: Salud Pública
Center, Department or Service: Universidad de Alicante. Departamento de Enfermería Comunitaria, Medicina Preventiva y Salud Pública e Historia de la Ciencia
Keywords: Synovial fluid | MSU | CPPD
Knowledge Area: Medicina Preventiva y Salud Pública
Issue Date: Dec-1989
Publisher: BMJ Publishing Group
Citation: PASCUAL, E.; TOVAR, J.; RUIZ, M.T.. “The ordinary light microscope: an appropriate tool for provisional detection and identification of crystals in synovial fluid”. Annals of the Rheumatic Diseases. Vol. 48, No. 12 (Dec. 1989). ISSN 0003-4967, pp. 983-985
Abstract: To determine if the ordinary light microscope is a useful tool in the detection and identification of crystals in synovial fluid 63 fluids (13 with monosodium urate (MSU), 14 with calcium pyrophosphate dihydrate (CPPD), one with both types of crystal, and 35 without crystals) were examined blindly by two observers, first with an ordinary light microscope, then with a polarising light microscope. Tentative identification of the crystals by their shape was attempted. The sensitivity of the ordinary light microscope for the detection of crystals was 96.2% and 100%, with specificity of 100% and 97.1% for observers 1 and 2, both with respect to the polarising light microscope. The concordance between observers for the ordinary light microscope was chi = 0.90 (0.897, 0.902) and for the polarising light microscope chi = 0.96 (0.958, 0.961). The specificity for identification of MSU and CPPD crystals by their shape with respect to the polarising light microscope was 92.3% and 85.7% for observers 1 and 2. When a polarising light microscope is not available examination of synovial fluid by an ordinary light microscope may allow a provisional diagnosis; definitive identification of the crystals requires a polarising light microscope.
URI: http://hdl.handle.net/10045/17848
ISSN: 0003-4967 (Print) | 1468-2060 (Online)
DOI: 10.1136/ard.48.12.983
Language: eng
Type: info:eu-repo/semantics/article
Rights: Annals of the Rheumatic Diseases. http://ard.bmj.com/
Peer Review: si
Publisher version: http://dx.doi.org/10.1136/ard.48.12.983
Appears in Collections:INV - SP - Artículos de Revistas
Institucional - IUIEG - Publicaciones

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