Acute lymphoblastic leukaemia among Spanish children and mothers' occupation: a case-control study

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Campo DCValorIdioma
dc.contributorSalud Públicaen
dc.contributor.authorInfante-Rivard, Claire-
dc.contributor.authorMur, Patricia-
dc.contributor.authorArmstrong, Ben-
dc.contributor.authorÁlvarez-Dardet, Carlos-
dc.contributor.authorBolúmar Montrull, Francisco-
dc.contributor.otherUniversidad de Alicante. Departamento de Enfermería Comunitaria, Medicina Preventiva y Salud Pública e Historia de la Cienciaen
dc.identifier.citationINFANTE-RIVARD, Claire, et al. "Acute lymphoblastic leukaemia among Spanish children and mothers' occupation: a case-control study". Journal of Epidemiology and Community Health. Vol. 45, No. 1 (March 1991). ISSN 0143-005X, pp. 11-15en
dc.description.abstractSTUDY OBJECTIVE: The aim was to investigate the association between mothers' occupational exposure during pregnancy and the incidence of acute lymphoblastic leukaemia in children. DESIGN: The study was a case-control investigation. A face to face interview was used to assess exposures at work and relevant confounding variables. SETTING: The study was community based and was carried out in five provinces of Spain. SUBJECTS: 128 cases less than 15 years of age were interviewed (91% of those eligible). Controls (one for each case) were chosen from the census lists and were matched on year of birth, sex and municipality. MEASUREMENTS AND MAIN RESULTS: Children of mothers working at home had a relative risk (RR) of 7.0 (95% CI = 1.59-30.79) of developing acute lymphoblastic leukaemia. Exposure to organic dust was associated with a RR of 5.5 (95% CI = 1.21-24.8). There was a statistically significant interaction between exposure to organic dust and working at home. The majority of women working at home were hired by local industries to sew different types of tissues (cotton, wool, synthetic fibres) on a machine. CONCLUSION: A similar association has not been reported before: if confirmed, this finding may suggest a new health concern.en
dc.publisherBMJ Publishing Groupen
dc.rightsJournal of Epidemiology & Community Health.
dc.subjectAcute lymphoblastic leukaemiaen
dc.subjectCase-control studyen
dc.subject.otherMedicina Preventiva y Salud Públicaen
dc.titleAcute lymphoblastic leukaemia among Spanish children and mothers' occupation: a case-control studyen
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