The default cyanobacterial linked genome: an interactive platform based on cyanobacterial linkage networks to assist functional genomics
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Título: | The default cyanobacterial linked genome: an interactive platform based on cyanobacterial linkage networks to assist functional genomics |
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Autor/es: | Labella, Jose I. | Llop Estevez, Antonio | Contreras, Asunción |
Grupo/s de investigación o GITE: | Transducción de Señales en Bacterias |
Centro, Departamento o Servicio: | Universidad de Alicante. Departamento de Fisiología, Genética y Microbiología |
Palabras clave: | Co-occurrence | Cyanobacteria | DUF | Functional genomics | Gene linkage | Synteny |
Área/s de conocimiento: | Genética |
Fecha de publicación: | jun-2020 |
Editor: | Wiley |
Cita bibliográfica: | FEBS Letters. 2020, 594(11): 1661-1674. doi:10.1002/1873-3468.13775 |
Resumen: | A database of cyanobacterial linked genomes that can be accessed through an interactive platform (https://dfgm.ua.es/genetica/investigacion/cyanobacterial_genetics/Resources.html) was generated on the bases of conservation of gene neighborhood across 124 cyanobacterial species. It allows flexible generation of gene networks at different threshold values. The default cyanobacterial linked genome, whose global properties are analyzed here, connects most of the cyanobacterial core genes. The potential of the web tool is discussed in relation to other bioinformatics approaches based on guilty‐by‐association principles, with selected examples of networks illustrating its usefulness for genes found exclusively in cyanobacteria or in cyanobacteria and chloroplasts. We believe that this tool will provide useful predictions that are readily testable in Synechococcus elongatus PCC7942 and other model organisms performing oxygenic photosynthesis. |
Patrocinador/es: | The authors thank the Spanish Government (MINECO) for grants BFU2015-66360-P and PEJ-2014-P-00298, the Conselleria d’Educació, Investigació, Cultura i Esport from the Generalitat Valenciana for grant PROMETEO/2017/129, and the University of Alicante for PhD fellowship (FPUUA59) to JIL. |
URI: | http://hdl.handle.net/10045/107301 |
ISSN: | 0014-5793 (Print) | 1873-3468 (Online) |
DOI: | 10.1002/1873-3468.13775 |
Idioma: | eng |
Tipo: | info:eu-repo/semantics/article |
Derechos: | © 2020 Federation of European Biochemical Societies |
Revisión científica: | si |
Versión del editor: | https://doi.org/10.1002/1873-3468.13775 |
Aparece en las colecciones: | INV - TSB - Artículos de Revistas |
Archivos en este ítem:
Archivo | Descripción | Tamaño | Formato | |
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Labella_etal_2020_FEBSLett_final.pdf | Versión final (acceso restringido) | 2,66 MB | Adobe PDF | Abrir Solicitar una copia |
Labella_etal_2020_FEBSLett_accepted.pdf | Accepted Manuscript (acceso abierto) | 21,25 MB | Adobe PDF | Abrir Vista previa |
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